Anavar

Steroid Common Name: Anavar
Steroid Chemical Name: Oxandrolone / Oxandrin
Steroid Class: Oral Anabolic Steroid

As an anabolic steroids Anavar (Oxandrolone) has two major advantages:

- it does not convert to estrogen which causes breast tissue (gynecomastia)

- it does not significantly influence normal testosterone production at low dosages (10mgs). If dosages are higher (as for any anabolic steroid) then the body feels that it has enough testosterone and it reduces production of the luteinizing hormone (LH) which no longer stimulates testosterone production, leading to testicular atrophy (shrinking).

Before the Controlled Substances Act was passed to restrict the production, sale, and usage of anabolic steroids, Anavar was popular among athletes athletes. It specificity targets the androgen receptor that, unlike many other steroids, has not been reported to cause stunted growth in younger users (because it doesn’t convert to estrogen) and used at a typical dose rarely caused noticeable masculine effects aside from stimulating muscle growth. Anavar is not easily metabolized into DHT or estrogen. A typical dose of 20-30 mg provided elevated androgen levels for up to 8 hours. And to increase its effectiveness, a bodybuilder typically “stacked” the drug with others such as Testosterone, to achieve even more body mass. Bodybuilders would consider a normal dose 20–30 mg a day, but in fact 10 mg of Anavar is more than enough. Higher dosages not only lead to Androgen Receptor downregulation and HPTA suppression but also damage the liver.

In part due to bad publicity from abuse by body builders and professional athletes, Anavar (Oxandrolone) was discontinued by it’s maker, Searle Laboratories, in 1989. It was picked up by the company now known as Savient Pharmaceuticals, Inc. who, following successful clinical trials in 1995, released it under the tradename Oxandrin.

In some studies, those treated with Anavar showed improved body composition and muscle mass. However, other studies have shown links between prolonged use and problems with liver toxicity. Even in small dosages users reported problems such as bloating, nausea, rash,  itching, hives, black/tarry stools or light-colored stools, depression, bleeding, swelling, jaundice, and diarrhea.

Anavar may increase the amount of LDL (‘bad cholesterol’) and decrease the amount of HDL ( ‘good cholesterol’) in the blood. This can increase the risk of heart disease. Anavar may damage the liver or increase LDL without causing symptoms. So if you intend on using Anavar it is important to have regular blood tests to be sure that the liver is working properly and that LDL has not increased. Anavar-Oxandrolone may also decrease fertility in men

References:

  1. Przkora R, Herndon DN, Suman OE (January 2007).
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